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The patients underlying conditions like diabetes should be taken into account to create a tailored approach to obesity and chronic weight management

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The potential benefits of glycemic control must be weighed against unknown fetal risks, with alternative diabetes management strategies typically preferred during pregnancy

Pharmacologically mediated marked initial maternal body weight loss and reductions in body weight gain and food consumption coincided with an increase in early pregnancy losses and led to delivery of slightly smaller offspring at 0.075 mg/kg twice weekly (2X human exposure)